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Eiji Sakai Selected Research

Aberrant Crypt Foci

6/2017The distribution of human rectal aberrant crypt foci and criteria for defining the counting area.
12/2015Association between factors associated with colorectal cancer and rectal aberrant crypt foci in humans.
9/2014Conditional knockout of the leptin receptor in the colonic epithelium revealed the local effects of leptin receptor signaling in the progression of colonic tumors in mice.
12/2012Relationship of human rectal aberrant crypt foci and formation of colorectal polyp: One-year following up after polypectomy.
9/2012Eicosapentaenoic acid (EPA) efficacy for colorectal aberrant crypt foci (ACF): a double-blind randomized controlled trial.
9/2012Number of aberrant crypt foci in the rectum is a useful surrogate marker of colorectal adenoma recurrence.
5/2012Natural history of human aberrant crypt foci and correlation with risk factors for colorectal cancer.
3/2012Metformin efficacy and safety for colorectal polyps: a double-blind randomized controlled trial.
1/2012Identification of preneoplastic lesions as mucin-depleted foci in patients with sporadic colorectal cancer.
9/2011Investigation of the prevalence and number of aberrant crypt foci associated with human colorectal neoplasm.
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Eiji Sakai Research Topics

Disease

13Colorectal Neoplasms (Colorectal Cancer)
02/2021 - 01/2010
12Neoplasms (Cancer)
09/2021 - 01/2010
12Aberrant Crypt Foci
06/2017 - 01/2010
11Hemorrhage
01/2021 - 05/2011
10Carcinogenesis
09/2014 - 01/2010
8Adenoma (Adenomas)
04/2021 - 01/2010
5Polyps
04/2021 - 10/2011
3Biliary Tract Neoplasms (Biliary Tract Cancer)
09/2021 - 01/2011
3Diabetes Mellitus
03/2012 - 01/2010
2Ulcer
01/2022 - 10/2012
2Iron-Deficiency Anemia (Anemia, Iron Deficiency)
04/2021 - 07/2011
2Type 2 Diabetes Mellitus (MODY)
03/2020 - 03/2012
2Anemia
06/2019 - 02/2017
2Obesity
09/2014 - 10/2011
2Chronic Renal Insufficiency
07/2013 - 01/2013
2Peptic Ulcer (Peptic Ulcers)
01/2012 - 07/2011
1Constipation
01/2022
1Sarcopenia
09/2021
1Melena
04/2021
1Esophageal Stenosis (Esophageal Stricture)
08/2020
1Stomach Neoplasms (Stomach Cancer)
08/2020
1Sclerosis
03/2020
1Non-alcoholic Fatty Liver Disease
03/2020
1Esophageal Neoplasms (Esophageal Cancer)
01/2020
1Pathologic Constriction (Stenosis)
01/2020
1Hypopharyngeal Neoplasms
01/2020
1Mesenteric Ischemia
10/2019
1Dehydration (Water Stress)
10/2019
1Neuroendocrine Tumors (Neuroendocrine Tumor)
01/2019
1Abdominal Pain (Pain, Abdominal)
11/2018
1Leiomyoma (Uterine Fibroids)
11/2018
1Diarrhea
11/2018
1Leiomyosarcoma
11/2018
1Fibrosis (Cirrhosis)
07/2017
1Bradycardia
07/2017
1Atrophy
01/2017
1Hemophilia A (Haemophilia)
12/2014
1Cardiovascular Diseases (Cardiovascular Disease)
09/2012
1Hyperlipidemias (Hyperlipidemia)
09/2012
1Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
01/2012
1Hypertension (High Blood Pressure)
01/2012
1Gastroesophageal Reflux (GERD)
01/2012
1Dyspepsia (Indigestion)
01/2012
1Myocardial Ischemia (Ischemic Heart Diseases)
01/2012
1Body Weight (Weight, Body)
01/2012

Drug/Important Bio-Agent (IBA)

8Biomarkers (Surrogate Marker)IBA
06/2017 - 01/2010
6Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
02/2017 - 01/2009
5Capsules (Microcapsules)IBA
06/2019 - 01/2011
5Pharmaceutical PreparationsIBA
07/2017 - 01/2010
4Leptin ReceptorsIBA
09/2014 - 02/2011
4LeptinIBA
09/2014 - 02/2011
3Metformin (Glucophage)FDA LinkGeneric
04/2016 - 09/2010
3Methylene Blue (Methylthioninium Chloride)FDA Link
12/2012 - 01/2012
2Bile Acids and Salts (Bile Acids)IBA
01/2022 - 01/2018
2Pioglitazone (Actos)FDA Link
03/2020 - 01/2010
2Biological ProductsIBA
06/2017 - 09/2011
2CarcinogensIBA
09/2014 - 10/2011
2BiguanidesIBA
03/2012 - 09/2010
2Omeprazole (Prilosec)FDA LinkGeneric
07/2011 - 07/2011
2GemcitabineFDA Link
03/2011 - 01/2011
1elobixibatIBA
01/2022
1Polyglycolic Acid (Polyglycolide)IBA
01/2022
1Prostaglandins AIBA
04/2021
1BariumIBA
04/2021
1Phenobarbital (Luminal)FDA Link
02/2021
16- ((4- ethylphenyl)methyl)- 3',4',5',6'- tetrahydro- 6'- (hydroxymethyl)spiro(isobenzofuran- 1(3H),2'- (2H)pyran)- 3',4',5'- triolIBA
03/2020
1Alanine Transaminase (SGPT)IBA
03/2020
1Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
10/2019
1LaxativesIBA
10/2019
1SolutionsIBA
10/2019
1IronIBA
06/2019
1antineoplaston A10 (A 10)IBA
11/2018
1Estrogen ReceptorsIBA
11/2018
1Hypnotics and Sedatives (Sedatives)IBA
07/2017
1Insulin (Novolin)FDA Link
12/2015
1Hemoglobins (Hemoglobin)IBA
11/2014
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
07/2013
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
09/2012
1Coloring Agents (Dyes)IBA
09/2012
1Eicosapentaenoic AcidIBA
09/2012
1milk-derived factorIBA
01/2012
1MucinsIBA
01/2012
1AcidsIBA
01/2012

Therapy/Procedure

5Chemoprevention
04/2016 - 01/2010
3Drug Therapy (Chemotherapy)
09/2021 - 01/2011
3Traction
02/2021 - 05/2020
3Endoscopes
08/2020 - 01/2020
3Therapeutics
03/2020 - 10/2011
3Argon Plasma Coagulation
06/2019 - 01/2007
1Time-to-Treatment
09/2021
1Endoscopic Hemostasis
01/2021
1Appendectomy
05/2020
1Blood Transfusion (Blood Transfusions)
06/2019
1Cautery
06/2019
1Ligation
01/2019
1Colectomy
11/2018
1Surgical Instruments (Clip)
01/2018
1Sutures (Suture)
07/2016
1Gastrostomy
12/2014
1Renal Dialysis (Hemodialysis)
01/2013